Histofreezer – Wart Removal System

The Histofreezer® is a form of Cryotherapy (treatment of conditions using various forms of liquid nitrogen). It is an FDA-approved treatment for wart removal.

Histofreeze treatment

How the histofreezer works

Liquid nitrogen, housed in a pressurised canister, is sprayed onto the affected area in a controlled manner. This area of the skin reaches a temperature of -55ºC.

The uppermost layer of the skin, together with the lesion, eventually drops off. A new, healthier layer of skin replaces it. This can take any time between 10 to 14 days depending on individual recovery.

Histofreezer treats a range of common lesions

Apart from its indicated use of wart removal, the Histofreezer can also help eliminate other benign skin growths found on the body:

  • Skin Tags
  • Genital Lesions
  • Actinic Keratosis
  • Seborrheic Keratoses
  • Molluscum Contagoisum and more.

Benefits of histofreezer

  • As a US FDA-approved treatment system, the efficacy of Histofreeze has been proven through clinical studies and use
  • Because the lesion is frozen off, any stinging or burning sensation felt during the treatment will rapidly fade away during the thawing phase

Safety of the histofreezer

The Histofreezer® allows targeted wart removal and treatment of benign lesions at temperatures warmer than -60ºC, reducing the chances of scarring. Histofreeze is safe for adults, and children 4 and over.


What is Histofreeze?

Histofreeze is a form of Cryotherapy that eliminates common skin growths such as warts, seborrhoeic keratosis and actinic keratosis. This is done via the Histofreezer® canister.

What can I expect from Histofreeze?

Depending on the size of the lesion and patient recovery, most lesions resolve after 3 treatments, once every two weeks.

How long is one Histofreeze tratment?

After assessing your needs, the doctor can get the Histofreeze done in a matter of minutes.

How long do the Histofreeze results last?

Upon completion of the recommended course, results can be permanent. Results vary by the individual and lifestyle choices. Repeated treatments may be required for some skin disorders.

is Histofreeze painful?

There may be slight blistering. Minor discomfort is common and can last for up to 2 days. This can be relieved with paracetamol.

Is there any downtime with Histofreeze?

The wound healing time can vary between a few days to a couple of weeks for larger areas. Patients with smaller, less prominent lesions usually return to daily activities after treatment.

Sometimes the area may swell up, blister and can fill with blood. This is quite normal following Histofreeze. Blisters can be pricked with a sterile needle and an antiseptic cream can be applied morning and evening until the healing process is complete.

If you feel the pain is not reducing after four or five days of the treatment, and the area looks red and angry, please inform our clinic.

In addition, temporary, visible changes in the intensity of pigmentation may occur following treatment such as hypopigmentation (turning white) or hyperpigmentation (turning dark).

Who's suitable for Histofreeze?

Histofreeze is safe for most healthy adults, and children over the age of 4. As with all medical procedures, you should be sure to disclose all of your medical history and current habits such as smoking and use of blood-thinners, medications, birth control pills, or supplements.

Who's unsuitable for Histofreeze?

Histofreeze is unsuitable in the following circumstances:

  • Lesions that are not benign. Find out by speaking to our doctor who will assess you in person
  • Those with a risk of leg ulcers and older patients should avoid Histofreeze on the gaiter area of legs

What are the pre & post-care instructions for Histofreeze?

Pre-care: Please shave any hair around the lesions the night before treatment. Longer, thicker hair can be in the way of treatment.

Post-care: Wash the treated area on a daily basis to keep the area clean and to gently remove any loose scabs. Avoid prolonged exposure of the treatment area to sunlight.

[20 Oct 2018] Written by Dr. Kelvin Chua

Dr Kelvin Chua – The Mentor
MBBS, Australia;
Certified Laser Physician,
Certified Laser Lipolysis Physician

Dr Kelvin Chua started his surgical training in Australia, teaching for several years in the hospitals, and spent time in dermatology and surgical rotations.

Over the course of 15 years, Kelvin has since performed more than 1,000 successful cases of liposuction procedures and Botox and filler treatments under his belt. With a keen interest in non-invasive facial contouring and lifting techniques as well as liposuction for body contouring procedures, he also performs HIFU, Thermage FLX, Fractional CO2 laser, Radiofrequency, hair loss management & treatment, as well as moles and lumps removal.

With a strong passion for inspiring others through teaching, Kelvin is a motivational speaker at Republic Polytechnic, an appointed trainer for aesthetic institutions and cosmeceutical companies, and is a mentor to aspiring aesthetic doctors.

For more information, write to
To contact Dr Kelvin Chua, write to