Due to regulatory guidelines, we are unable to list specific brand names on our website and have used replacement terms instead. To find out what these terms refer to, please contact us directly.
Due to regulatory guidelines, we are unable to list specific brand names on our website and have used replacement terms instead. To find out what these terms refer to, please contact us directly.
Due to regulatory guidelines, we are unable to list specific brand names on our website and have used replacement terms instead. To find out what these terms refer to, please contact us directly.

Re20 ECM Skinbooster

Re20 ECM Skinbooster Treatment Overview

3 sessions and above

6-12 months

Minimal downtime

30 minutes

What Is Re20 ECM Skinbooster

Re20 ECM Skinbooster is a skinbooster treatment that supports skin regeneration by replenishing the extracellular matrix (ECM), the network of proteins, glycosaminoglycans, and other molecules that maintain firmness, elasticity, hydration, and overall skin quality.

A healthy ECM is the foundation of youthful skin. It ensures collagen fibres form efficiently, supports elasticity, and optimises how skin responds to ageing, stress, and environmental damage. When the ECM weakens, collagen production slows, elasticity drops, and skin becomes dull, saggy, or prone to fine lines. By directly replenishing the ECM, Re20 acts like a smart shortcut to strong, resilient skin, helping to maximise the benefits of collagen and improve skin’s long-term health.

Its formulation is derived from micronised human acellular dermal matrix (hADM) and includes:

89%

Collagen

provides firmness and tensile strength

3%

Elastin

provides elasticity and resilience

0.4%

Glycosaminoglycans

including hyaluronic acid, supporting hydration and nutrient transport

7.6%

Other ECM proteins

such as fibronectin, laminin, and tenascin to support tissue architecture

This composition closely resembles youthful human skin, allowing natural integration with existing ECM.

How Re20 ECM Skinbooster Supports Skin Regeneration

Re20 works in two phases:

Phase 1: Immediate Integration
Once injected, ECM components integrate with the native dermal matrix, improving skin thickness, texture density, and hydration almost immediately.

Phase 2: Regenerative Activation
Over 1-12 weeks, the supplemented ECM acts as a scaffold, signalling fibroblasts to produce new collagen, elastin, and ECM proteins. This leads to:

  • Rebuilding of collagen and elastin fibres
  • Improved hydration and nutrient flow
  • Strengthened dermal structure
  • Enhanced firmness and elasticity

Benefits of Re20 ECM Skinbooster For Your Skin

By directly supplementing the extracellular matrix, Re20 helps restore the skin’s internal framework rather than only stimulating surface collagen. This supports healthier skin behaviour over time and improves how skin responds to ageing and treatments. Key benefits include:

  • Increased collagen and elastin levels, supporting stronger and more elastic skin
  • Noticeable reduction in pore appearance
  • Improvement in skin texture density and smoothness
  • Reduction in redness, pigmentation irregularities, and uneven tone
  • Enhanced skin elasticity and regenerative response
  • Improved skin radiance and overall clarity
  • Reduction in fine lines and skin roughness over time

Clinical evaluations show that Re20 supports measurable improvements across multiple skin quality indicators, such as: 

  • Pore size reduction of up to 26.9%
  • Reduction in pigmentation and skin blemishes by up to 11.5%
  • Improvement in skin texture density by up to 9%
  • Reduction in skin redness and melanin levels by up to 27.6%
  • Enhanced skin elasticity and regeneration, confirmed through elasticity measurements

By preserving the skin’s natural extracellular matrix structure while encouraging new ECM formation, Re20 supports gradual, sustained improvements in overall skin quality rather than short-term surface effects.

What Makes Re20 ECM Skinbooster Different

Re20 works at the root of skin ageing by directly replenishing the extracellular matrix, giving the skin a stronger foundation rather than simply hydrating or stimulating it.

  • Re20 restores the ECM directly rather than mimicking or stimulating components.
  • Addresses multiple signs of ageing at once, including texture, tone, firmness, and hydration.
  • Works without adding volume, unlike dermal fillers.
  • Can enhance results of other treatments by strengthening the skin’s foundation.

Who Is Re20 ECM Skinbooster For

Re20 may be suitable for those who:

  • Notice early to moderate signs of ageing
  • Want firmer, smoother, and more radiant skin
  • Have enlarged pores, uneven tone, or fine lines
  • Prefer treatments with minimal downtime
  • Seek improvements that go beyond surface hydration
  • Want something beyond short-term results

A consultation with our doctors is recommended to assess suitability and personalise a treatment plan.

Which Areas Can Re20 ECM Skinbooster Treat?

Re20 supports multiple facial and décolletage areas by strengthening the skin’s structure and improving overall skin behaviour, including:

It addresses multiple concerns, including wrinkles, sagging, reduced elasticity, dullness, enlarged pores, uneven tone, and post-procedure skin recovery.

Re20 ECM vs HA Skinboosters vs PN Skinboosters vs Collagen Stimulating Skinboosters

While both Re20 ECM and conventional skin boosters aim to improve skin quality, they work in different ways and target different layers of the skin. Key distinctions include:

Feature

Re20 ECM Skinbooster

HA Skin Boosters

PN Skin Boosters 

Collagen-Stimulating Skin Boosters

Core Function

Directly replenishes extracellular matrix (ECM) components

Provides hydration and improves skin glow

Supports skin repair and reduces inflammation

Stimulates the skin to produce new collagen

Main Active Focus

Collagen, elastin, glycosaminoglycans, and other ECM proteins

Hyaluronic acid

Polynucleotides (DNA fragments)

Biostimulatory agents (PDLLA, PCL, CaHA)

Depth of Action

Dermal layer, supporting overall skin structure

Mainly superficial to mid-dermis

Mid-dermis

Mid to deep dermis

Primary Skin Benefits

Improves skin firmness, elasticity, texture, hydration, and overall skin quality

Enhances hydration, smoothness, and radiance

Calms sensitive skin and supports tissue repair

Improves firmness, contour, and skin density

Effect on Skin Structure

Supports and replenishes the skin’s existing ECM framework

Does not directly rebuild deeper skin structure

Supports repair but does not directly restore ECM components

Stimulates collagen production but does not directly restore ECM components

Volume Effect

No volume added

No volume added

No volume added

May add subtle volume depending on formulation

Best Suited For

Early to moderate ageing, long-term skin quality support, and treatment maintenance

Dehydrated skin and mild surface-level concerns

Sensitive, inflamed, or compromised skin

Skin laxity, firmness loss, and contour concerns

Longevity of Results

Gradual and sustained improvements over months

Short to medium term

Medium term

Medium to long term

Results, Downtime, and Treatment Schedule

Results

Downtime

Treatment Schedule

Progressive improvement in texture, elasticity, hydration, and overall skin quality as ECM rebuilding continues.

Minimal; mild redness, small bumps, or slight swelling may occur but typically resolves within 24-48 hours.

Most commonly 3 initial sessions spaced 1 month apart. Additional sessions may be recommended depending on skin condition and goals. Maintenance may be advised every 6-12 months.

How Much Is Re20 ECM Skinbooster?

Re20 ECM Skinbooster starts from $950 per session. Final recommendations will be discussed during your consultation depending on treatment area, session count and individual needs.

Start Rebuilding Your Skin’s Foundation Today

To find out whether Re20 ECM Skinbooster is suitable for your skin concerns and goals, speak to our doctors or book a consultation.

Interested?

Contact Us

FAQ

Re20 ECM Skinbooster is developed using human acellular dermal matrix (hADM), a material that has been used safely for decades in reconstructive surgery and regenerative dermatology. It is carefully processed to ensure it is compatible with the skin and to minimise the risk of unwanted reactions.

The product meets recognised international standards and is AATB-accredited, FDA-listed, and MFDS-registered, providing additional reassurance around its safety and quality.

No. It replenishes ECM components directly, rather than only hydrating or stimulating collagen.

Discomfort is minimal. Numbing cream will be applied.

Some improvement may be visible immediately, with progressive results over the next few weeks.

Typically 6–12 months, depending on skin condition and maintenance.

Downtime is minimal. Mild redness or swelling usually settles within 1–2 days.

Yes. Re20 can be paired with lasers, RF, HIFU, and injectables to enhance overall outcomes.

A personalised consultation is required to determine suitability based on skin type and goals.

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