Juvelook vs Profhilo: Which is the Safer Choice?
TL;DR
- Both Juvelook and Profhilo stimulate collagen, but Profhilo is gentler and safer.
- Juvelook uses Poly-D-Lactic Acid (PDLLA), while Profhilo uses biocompatible Hyaluronic Acid (HA), resulting in a different safety profile.
- PDLLA in Juvelook may lead to longer-term complications; for that reason, Profhilo is a safer and more effective choice for skin rejuvenation.
Table Of Contents
Injectable collagen stimulators have rapidly reshaped the beauty landscape, becoming a go-to choice for those looking to keep their skin smooth and youthful.
Two key brands, Juvelook and Profhilo, have gained considerable popularity, each offering unique approaches to anti-ageing.
While both treatments aim to firm and rejuvenate skin, understanding their differences, especially when it comes to safety, is essential.
In this article, we will look at why, despite Juvelook’s long-lasting effects, Profhilo stands out as a safer alternative, especially for beginners prioritising a low-risk yet high-reward experience.
How Juvelook and Profhilo Work
Although Juvelook and Profhilo both stimulate collagen, they do so in very different ways.
As a hybrid skin booster, Juvelook has two key components:
- 7I .5% Non-Crosslinked Hyaluronic Acid (HA): Immediate hydration and plumpness to give skin a natural, youthful look.
- Poly DL-lactic Acid (PDLLA): Long-term collagen production that improves skin structure and reduces signs of ageing over time.
PDLLA is known for its ability to stimulate collagen synthesis, promote tissue regeneration, and reverse skin degradation. However, its synthetic nature means it takes longer to break down and could lead to complications.
Profhilo, on the other hand:
- Targets skin laxity through the production of elastin and collagen
- Has one of the highest concentrations of hyaluronic acid (32 mg/mL) in the market (5x more than the typical skinbooster).
- Contains L-HA and H-HA—This HA hybrid enables hyaluronic acid to be released for a longer time for more efficient bio-remodeling.
- Offers patented NAHYCO® technology that disperses hyaluronic acid smoothly without the immune response that synthetic materials can provoke, making it a gentler option for bio-remodelling.
- It was launched in 2015 in Italy. The few adverse reactions reported are primarily due to hypersensitivity or incorrect injection techniques, not due to the product itself. Profhilo’s popularity comes from a strong safety profile and bio-compatibility[1].
While Profhilo in Singapore is generally well-tolerated, some mild and temporary side effects may occur from treatment, including oedema, pain, erythema, itching, bleeding, and ecchymosis, which generally resolve within a week[1].
The Lesser-Known Side Effects of PDLLA Injections Like Juvelook
While collagen-stimulating injectables generally offer safe and effective results, PDLLA-based ones tend to have a higher chance of developing side effects like nodules.
These nodules, which are caused by an exaggerated inflammatory reaction, also typically appear 6-24 months after treatment. They can grow to the size of a bean or larger and often require extensive treatment to resolve.
Other complications include:
- Filler migration, which can be common and lead to facial asymmetry
- Swelling and, in severe cases, multifocal strokes and vision loss
Effective management of these complications involves an early diagnosis and prompt treatment (e.g. topical or intralesional corticosteroids). Engaging a doctor with good techniques and experience is vital in preventing nodule formation and other risk factors, as is ensuring that your clinic pays close attention to pre and post-treatment for any potential adverse reactions.
Why Do Side Effects With PDLLA Happen?
PDLLA side effects can occur for a variety of reasons, such as:
- Uninformed patient selection or content—This is crucial. During your consultation, your doctor should discuss your medical history and proclivities to ensure you are an appropriate candidate for PDLLA injections.
- Incorrect or uneven injection procedures—This can introduce air bubbles into the bloodstream (causing vision loss and multifocal strokes).
- Inexperienced practitioners—Without proper training or experience, doctors put their patients at higher risk of filler migration, facial asymmetry, swelling and inflammatory responses.
For those with busy lifestyles, managing complications like granulomas can require additional time and effort, so lower-risk alternatives might be a better choice.
Why Profhilo Is a Safer Choice
Profhilo’s appeal lies in its twofold benefits: intense hydration and biostimulation, achieved without fillers or complex polymers like PDLLA. Its high concentration of hyaluronic acid revitalises skin, enhancing elasticity and firmness with less risk.
Profhilo also has anti-inflammatory properties that can restore and regenerate tissue, and can be very helpful for conditions associated with dry skin, such as rosacea and eczema.
Following Profhilo treatment, you may notice small bumps—similar to insect bites or mild swelling—at injection sites. These are not the same as granulomas and usually subside within 24-48 hours.
Like all injectables, Profhilo can have side effects such as bruising and swelling, but these are often due to the use of needles, not the product itself.
Also Read: The Truth Behind Collagen Supplements & Stimulators
Conclusion: Choosing What’s Best for You
Though both Juvelook and Profhilo stimulate collagen, they do so in distinct ways that affect safety and outcome. Juvelook’s PDLLA promotes extended collagen production, making it popular if you are seeking longer-term effects.
However, the risks of PDLLA mean Juvelook may not suit everyone. Profhilo, with its hyaluronic acid-driven approach, promotes collagen synthesis and skin elasticity in a more gentle, non-invasive way, which is ideal if you value safety and efficacy.
Consult us today to choose the best bio-remodelling treatment for your needs and aesthetic goals.
