Profhilo Treatment In Singapore Complete Guide - Price, Cost & FAQs

“Do you know what truly happens to your skin as you age?”

Well, they begin to lose collagen.  Progressively, your skin also starts to lose its natural hyaluronic acid content. Hyaluronic acid is a crucial element in prolonging the lifespan of our skin cells — it contributes to our skin’s overall barrier function and helps our skin to retain moisture effectively! Since this hyaluronic acid content depletes as we age, our cells will not be able to retain water as effectively, leading to a breakdown in our skin’s collagen and elasticity over time. Hence, PROFHILO® treatment is an option widely used throughout Europe and now Singapore to replenish our skin’s hyaluronic acid content and restore our skin’s youthful appearance.

In this article, let’s dig deeper into all you need to know about PROFHILO® in Singapore!

How does PROFHILO® work?

As you age, your body starts to produce less collagen and elastin – the cells that give your skin its structure and firmness. This means your skin can no longer hold its appearance and the first signs of ageing, such as fine lines and wrinkles, start to appear.

PROFHILO® works right at the root cause of the problem – stimulating collagen and elastin production and increasing the elasticity of your skin. PROFHILO® is a BDDE-free stabilised injectable hyaluronic acid (HA)-based product that is injected to treat skin laxity among many other skin issues.

Is hyaluronic acid safe for the body?

Hyaluronic acid occurs naturally, and the levels of HA in the body are balanced by an enzyme known as hyaluronidase, which breaks down the hyaluronic acid molecules.

Fun fact:
Hyaluronidase is also the substance that breaks down PROFHILO® fillers over time, making it less disruptive than most other forms of fillers. That’s because your body is already equipped with hyaluronidase to work with the main ingredient, hyaluronic acid!

With one of the highest concentrations of HA on the market (64mg / 2ml) PROFHILO® is not only boosting and hydrating the skin, but also remodels the ageing and sagging tissue.

What are the benefits of PROFHILO® Treatment?

PROFHILO® offers safe and effective skin rejuvenation for patients looking to improve skin quality, hydration and restore radiance.

It’s an effective alternative to surgical treatments

PROFHILO® is an excellent treatment with outcomes without the invasive and often permanent effect of surgical treatments.

It fights against skin laxity

PROFHILO® triggers the production of elastin to regain the firmness and suppleness of the skin around the injected site. The treatment processes in a manner where collagen and elastin fibres are remodelled on the dermal matrix and counteract skin laxity instantly. This means that you can say goodbye to skin laxity issues as PROFHILO® treatment would tighten your skin and make it appear as fresh as ever.

It improves the quality of your skin

For patients experiencing wrinkles, crepiness, or loose skin, PROFHILO® treatment boosts your skin to make it appear clear, spotless, and flawless. By tightening your skin, it produces a lifting effect that gives you a younger and fresher look.

It allows patients to specifically target problematic areas

Most people face issues on specific parts of their face, such as under eye wrinkles, crepey cheeks, or fine lines that surround the eyes. The PROFHILO® treatment is excellent in targeting these areas and it ensures that each area is fully treated. Apart from this, it also caters to the needs of your neck or hands by tightening them and making them appear smooth.

It also improves your skin’s texture and its tone

Not only does the PROFHILO® treatment remove unwanted marks or dents from your skin but it also improves its texture by softening it. Moreover, PROFHILO® treatment is an ideal strategy to improve your skin tone. It also cleans your skin by removing oils and burns you have had previously and improves your skin tone by exposing your original skin colour. Overall, PROFHILO® clears your skin, your skin tone, and the texture of your skin.

How do I decide if PROFHILO®is right for me?

PROFHILO® skin treatments are most commonly undertaken by women and men over the age of 30 who are experiencing the early signs of saggy skin, wrinkles, and dehydrated, dull or sunken skin. This typically happens when the hyaluronic acid, collagen and elastin that our bodies produce when we are younger begins to disappear as we age, leaving ageing skin looking tired, saggy and creased.

At SL Aesthetic Clinic, we believe there is no shame to seeking cosmetic treatments! That’s why we’ve helped many who feel self-conscious about these skin ageing changes, especially when they are premature. There is no upper age limit for PROFHILO® skin treatments and it is suitable for reversing and repairing many ageing symptoms.

However, it is worth noting that for those over the age of 60 who have accelerated ageing skin, the treatment may see varied results compared to combined treatments with other methods. This is largely due to elderly skin having deeper folds to penetrate. Hence, PROFHILO® skin treatments is ideal for individuals who experience early signs of the following:

  • Wrinkles (e.g smokers lines, frown lines, crows feet)
  • Saggy and excess skin
  • Dry, dehydrated skin
  • Skin that has lost elasticity and shape

Since PROFHILO® is an injection that mimics the body’s production of hyaluronic acid, the treatments are far more subtle than other dermal fillers which create a more dramatic change and lift. Therefore, if you’re looking for a subtle treatment that provides youthful and rejuvenating results, PROFHILO® might be the right fit for you. However, if you’re looking for a more drastic lift and remodelling treatment, you may want to look into dermal fillers or finding more advanced surgical procedures to get your desired results.

What are the differences between PROFHILO® and other treatments?

As compared to other skin boosters, the PROFHILO® achieves a variety of skin-boosting results. Here’s quick comparison table between PROFHILO®

InjectableHyaluronic Acid ContentFrequencyEffectsEstimated Pain LevelNumber of injectionsTreatment areas
2ml per syringe
2 sessions with minimum 1 month apartHydration
Increases Volume
Improve Skin Quality
Reduce Skin Laxity
2/105 points on each side of faceFace, neck, arms, hands, decolletae
Skin boosters


1ml per syringe

3 sessions, 1 month apartHydration
Skin Brightening
4/10Up to 100 points on whole faceFace, neck, hands
Rejuran Healer


2ml per syringe

3 sessions, a month apartImprove Skin Quality
No hydrating effect
6/10Up to 100 points on whole faceFace, neck, decolletage

Is there downtime for PROFHILO® Treatment?

Immediately after the procedure, you can see small bumps, much like an insect bite or bee sting, at the site of the injection. It may take up to 24 hours to settle.

It’s not really something that anyone else would notice. On the other hand, it is not a treatment to do a few hours before getting married or attending an important event.

Depending on what sort of skin you have you can still have a few bumps hanging around the following day.

The injection technique used during treatment means that only 5 small injections are needed on each side of the face meaning that the treatment is quick and comfortable.

PROFHILO® Treatment Prices in Singapore

At SL Aesthetic Clinic, we believe you should also be aware of the costs of PROFHILO® before you commit to it!

Here’s how PROFHILO® treatments work in general:

  • One syringe is required per treatment session.
  • One PROFHILO® pre-filled syringe is 2mls of volume.
  • The first 2 sessions are done 1 month apart, and maintenance treatment is every 6-9 months.

SL Aesthetic Clinic offers PROFHILO® treatments for between $1000-$1200 per syringe, depending on your case.This is in line with the average PROFHILO® Singapore prices of between $1000 – $1500.

Here’s a key note you need to know: there are plenty of fake or inauthentic PROFHILO® products in the market. Hence, it is important to ask any clinic to prove the authenticity of the PROFHILO® syringe before injecting.

At SL Aesthetic Clinic, we only use 100% authentic PROFHILO® injections. We believe in price transparency and adhere to the highest standards of safety.

Get started with PROFHILO® treatments for youthful, rejuvenated skin at SL Aesthetic Clinic

Like it or not, your skin is often the source of your confidence. When you wake up with great skin in the morning, it’s hard not to stay upbeat and positive throughout the day!

That’s why you should start your journey to smoother, youthful today.

With our panel of medically-trained and certified doctors recognised by the Singapore Medical Council’s Aesthetic Practice Oversight Committee (APOC), you’re in safe and able hands!

Walk-in or call us at +65 9850 71112 to start your journey to the skin you desire and deserve!


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To put it simply, PROFHILO® is injected under the skin using very small needles.

The protocol for PROFHILO® on the face requires it to be injected on 5 points each side of the face. The process is made more comfortable with numbing cream applied prior to the procedure. 

Slight soreness around the injection points can sometimes be felt for the first 1-2 days.

Hyaluronic Acid is well-tolerated by the skin. The only reported side effects are mild bruising and mild swelling at the injection sites. 

These generally disappear in a short period of time and are associated with the needle, not the product.

PROFHILO® was launched in February 2015 in Italy. It has been used worldwide ever since and has become a firm favourite across the globe with no adverse reactions reported.

From a safety perspective, PROFHILO® is highly bio-compatible because it is made from natural Hyaluronic Acid. It is also stabilised without the addition of chemical cross-linking agents.

This reduces the risk of adverse reactions. In any case, you should plan your treatments around social events in case you do experience any effects that could affect your appearance, such as mild bruising.

The PROFHILO® continues to work in the skin for around a month after treatment, at which point it will have been fully metabolised by the body.

By this time, it will have stimulated natural collagen and elastin production, meaning that the rejuvenating effects of treatment will continue even after PROFHILO® has been naturally broken down.

After initial treatments, a PROFHILO® treatment every six months should be sufficient to maintain the benefits.

Patients may feel an immediate improvement thanks to the hydrating effect, but it can take a few weeks before the real results of treatment start to be noticed as PROFHILO® encourages the body to produce its own anti-ageing collagen and elastin.

After a month, your skin should feel smooth, soft, tight and plump. At this point a second treatment is needed to stimulate the collagen fully and elastin production for optimal results.

You may notice a refreshed appearance even a week after your treatment. However, the full results can be seen 4 weeks after your second treatment.

Although it’s most commonly used on the face, it can also work well on the neck, arms, knees and hands.

PROFHILO® can be used alongside many of our other treatments, to further enhance the rejuvenating benefits. 

For example, PROFHILO® is a suitable partner for Botox treatments.

While Botox tackles wrinkles caused by specific muscles, PROFHILO® will give an overall radiance boost, complimenting the Botox.

Dermal fillers can also be used in conjunction with PROFHILO® to add volume to specific areas while PROFHILO® provides more general rejuvenation.

  • Makeup should not be worn for 12 hours.
  • Avoid alcohol and vigorous exercise for 48 hours.
  • Avoid sunbathing, and extremes of heat or cold for 14 days post treatment.
  • It is advisable to avoid aspirin for 12-48 hours after treatment.

PROFHILO® treatment takes around 30 minutes to be completed, per session.

During this half an hour period, the practitioner will apply numbing cream, mark out spots for injections and will inject your area of concern in five places for widespread and more effective treatment.

Generally, the procedure is quicker than most beauty procedures and is relatively comfortable.

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