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Profhilo Treatment In Singapore Complete Guide - Price, Cost & FAQs

“Do you know what truly happens to your skin as you age?”

Well, it begins to lose collagen. Progressively, your skin also starts to lose its natural hyaluronic acid content. 

Hyaluronic acid contributes to our skin’s overall barrier function and helps our skin to retain moisture effectively. Since this hyaluronic acid content depletes as we age, our cells will not be able to retain water as effectively, leading to a breakdown in our skin’s collagen and elasticity over time. 

PROFHILO® treatment is an option widely used throughout Europe and now Singapore to replenish our skin’s hyaluronic acid content and restore our skin’s youthful appearance.

How does PROFHILO® work?

As you age, your body starts to produce less collagen and elastin – the cells that give your skin its structure and firmness. This means your skin can no longer hold its appearance and the first signs of ageing, such as fine lines and wrinkles, start to appear.

PROFHILO® addresses this problem directly by stimulating collagen production and increasing elasticity of the skin. PROFHILO® is a BDDE-free stabilised injectable hyaluronic acid (HA)-based product that is injected to treat skin laxity among many other skin issues.

Is hyaluronic acid safe for the body?

Hyaluronic acid occurs naturally, and the levels of HA in the body are balanced by an enzyme known as hyaluronidase, which breaks down the hyaluronic acid molecules.

Fun fact:
Hyaluronidase is the least disruptive among other forms of fillers – it also happens to be the substance that breaks down PROFHILO fillers.

With one of the highest concentrations of HA on the market (64mg / 2ml) PROFHILO® not only boosts and hydrates skin, but also remodels ageing and sagging tissue.

A new version of PROFHILO®, PROFHILO® Structura, is slated to launch in end 2024. PROFHILO® Structura is anticipated to be an improved version with enhanced hydrating properties. 

What are the benefits of PROFHILO® Treatment?


PROFHILO® offers safe and effective skin rejuvenation for patients looking to improve skin quality, hydration and restore radiance.

It is a good starter treatment for those new to aesthetics

PROFHILO® is a non-invasive treatment that is very natural – from the way it works to the results it produces. Profhilo encourages your body to produce collagen so your body will never ‘overreact’. As such, Profhilo is a great entry treatment for those who are not ready for injectables like Botox and fillers. 

It fights against skin laxity

PROFHILO® triggers the production of elastin to regain the firmness and suppleness of the skin around the injected site. The treatment processes in a manner where collagen and elastin fibres are remodelled on the dermal matrix and counteract skin laxity instantly. This means that PROFHILO® treatment would tighten your skin and make it appear fresh.

It improves the quality of your skin

For patients experiencing wrinkles, crepiness, or loose skin, PROFHILO® treatment can help with a lifting effect. Read more about PROFHILO®’s lifting properties here

It allows patients to specifically target problematic areas

Most people face issues on specific parts of their face, such as under eye wrinkles, crepey cheeks, or fine lines that surround the eyes. The PROFHILO® treatment is excellent in targeting these areas and it ensures that each area is fully treated. Apart from this, it also caters to the needs of your neck or hands by tightening them and making them appear smooth.

It improves your skin’s texture and its tone

Not only does PROFHILO® treatment remove unwanted marks or dents from your skin it also softens skin texture. Moreover, PROFHILO® treatment is an ideal strategy to improve your skin tone. It cleans your skin by removing oils and burns you have had previously and improves your skin tone by exposing your original skin colour. Overall, PROFHILO® clears your skin, your skin tone, and the texture of your skin.

It contains anti-inflammatory properties 

PROFHILO® is a bio-remodelling agent that restores and regenerates tissue and improves the overall quality of skin. It carries anti-inflammatory properties, and can be beneficial for inflammatory conditions like rosacea and eczema. 

How is PROFHILO® injected?

PROFHILO® is conventionally injected using the Bio Aesthetic Points (BAP) technique, which identifies five injection points on each side of the face. However, newer research shows that PROFHILO® can be injected into the forehead and temples via a new technique using a cannula. This technique is reported to improve skin firmness, skin brightness and even eyebrow ptosis. 

How do I decide if PROFHILO® is right for me?

PROFHILO® skin treatments is ideal for individuals who experience early signs of the following:

  • Wrinkles (e.g smokers lines, frown lines, crows feet)
  • Saggy and excess skin
  • Dry, dehydrated skin
  • Skin that has lost elasticity and shape



Since PROFHILO® is an injection that mimics the body’s production of hyaluronic acid, it produces subtle instead of dramatic results. However, if you’re looking for a more drastic lift and remodelling treatment, you may want to look into dermal fillers or finding more advanced surgical procedures to get your desired results.

For those over the age of 60 who with accelerated ageing skin, the treatment may see varied results compared to combined treatments with other methods. 

Is there downtime for PROFHILO® Treatment?

Immediately after the procedure, you can see small bumps, much like an insect bite or bee sting, at the site of the injection, which may take up to 24 hours to settle.

While these bumps are not extremely obvious, we do not recommend doing PROFHILO treatment right before an important event.

Depending on what sort of skin you have you can still have a few bumps hanging around the following day.

The treatment process is quick and comfortable, requiring only 5 injection points on each side of the face.

PROFHILO® Treatment Prices in Singapore

  • One syringe is required per treatment session.
  • One PROFHILO® pre-filled syringe is 2mls of volume.
  • The first 2 sessions are done 1 month apart, and maintenance treatment is every 6-9 months.

SL Aesthetic Clinic offers PROFHILO® treatments for between $1000-$1200 per syringe, depending on your case.This is in line with the average PROFHILO® Singapore prices of between $1000 – $1500.

Note: There are plenty of fake or inauthentic PROFHILO® products in the market. Hence, it is important to ask any clinic to prove the authenticity of the PROFHILO® syringe before injecting.

At SL Aesthetic Clinic, we only use 100% authentic PROFHILO® injections. We believe in price transparency and adhere to the highest standards of safety.

Get started with PROFHILO® treatments for youthful, rejuvenated skin at SL Aesthetic Clinic

Like it or not, your skin is often the source of your confidence. When you wake up with great skin in the morning, it’s hard not to stay upbeat and positive throughout the day!

That’s why you should start your journey to smoother, youthful today.

With our panel of medically-trained and certified doctors recognised by the Singapore Medical Council’s Aesthetic Practice Oversight Committee (APOC), you’re in safe and able hands!

Walk-in or call us at +65 9850 71112 to start your journey to the skin you desire and deserve!


Contact Us


PROFHILO® is injected under the skin using very small needles. We use TSK INViSIBLE needles, which are 33% thinner than 30G needles. These ‘invisible’ needles are very comfortable, which makes Profhilo treatment (or any injectable treatment) with us almost painless.

The protocol for PROFHILO® on the face requires it to be injected on 5 points each side of the face. We use local anaesthesia and the process is made more comfortable with numbing cream. We also use a vibrating face tool that distracts patients from any pain sensations.

Slight soreness around the injection points can sometimes be felt for the first 1-2 days.

At our clinic, we’ve developed a proprietary protocol for our PROFHILO® treatment that incorporates local anaesthesia, ensuring a nearly painless experience for our clients. Please note that separate charges for anaesthesia may apply. 

Hyaluronic Acid is well-tolerated by the skin. The only reported side effects are mild bruising and mild swelling at the injection sites.

These generally disappear in a short period of time and are associated with the needle, not the product.

PROFHILO® was launched in February 2015 in Italy. It has been used worldwide ever since and has become a firm favourite across the globe with no adverse reactions reported.

From a safety perspective, PROFHILO® is highly bio-compatible because it is made from natural Hyaluronic Acid. It is also stabilised without the addition of chemical cross-linking agents.

This reduces the risk of adverse reactions. In any case, you should plan your treatments around social events in case you do experience any effects that could affect your appearance, such as mild bruising.

PROFHILO® continues to work in the skin for around a month after treatment, at which point it will have been fully metabolised by the body.

By this time, it will have stimulated natural collagen and elastin production, meaning that the rejuvenating effects of treatment will continue even after PROFHILO® has been naturally broken down.

For optimal results, we suggest scheduling an initial treatment followed by a second session one month later, a third session six to nine months after the second, and another session one month thereafter.

For drier, more matured skin, we recommend three treatments spaced one month apart initially, followed by a fourth session six to nine months later, and another two more sessions spaced one month apart. 

Please note that this is just a general guideline and our doctors can recommend better after an assessment. 

Patients may feel an immediate improvement thanks to the hydrating effect, but it can take a few weeks before the real results of treatment start to be noticed as PROFHILO® encourages the body to produce its own anti-ageing collagen and elastin.

After a month, your skin should feel smooth, soft, tight and plump. At this point a second treatment is needed to stimulate the collagen fully and elastin production for optimal results.

You may notice a refreshed appearance even a week after your treatment. However, the full results can be seen 4 weeks after your second treatment.

Although it’s most commonly used on the face, it can also work well on the neck, arms, knees and hands.

PROFHILO® can be used alongside many of our other treatments, to further enhance the rejuvenating benefits.

For example, PROFHILO® is a suitable partner for Botox treatments.

While Botox tackles wrinkles caused by specific muscles, PROFHILO® will give an overall radiance boost, complimenting the Botox.

Dermal fillers can also be used in conjunction with PROFHILO® to add volume to specific areas while PROFHILO® provides more general rejuvenation.

  • Makeup should not be worn for 12 hours.
  • Avoid alcohol and vigorous exercise for 48 hours.
  • Avoid sunbathing, and extremes of heat or cold for 14 days post treatment.
  • It is advisable to avoid aspirin for 12-48 hours after treatment.

PROFHILO® treatment takes around 30 minutes to be completed, per session.

During this half an hour period, the practitioner will apply numbing cream, mark out spots for injections and will inject your area of concern in five places for widespread and more effective treatment.

Generally, the procedure is quicker than most beauty procedures and is relatively comfortable.

Yes, PROFHILO® and Rejuran can be done together as they work synergistically. However, they should be done strategically for maximum results. If you are interested in a holistic PROFHILO® and Rejuran combination treatment plan, please contact us for more information. 

Yes, we recommend doing PROFHILO® after laser treatment to enhance skin hydration. Both treatments work synergistically for optimal skin rejuvenation effects. 

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