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Our outlets will be closed from 26 Mar (Tue) to 27 Mar (Wed) for our annual team bonding event. We will resume operations on 28 Mar (Thu).

A Guide to Rejuran Healer in Singapore: Treatment, Price, Risks & Side Effects

A Guide to Rejuran Healer Price, Risks & Side Effects

Sagging skin. Fine lines. Wrinkles. The changes in our skin can be a downer as they become more apparent with age. While we can’t turn back time, we can take some steps to keep our skin healthier for longer.

That’s where a treatment like Rejuran in Singapore comes into play. It aids the body’s production of collagen and elastin, the proteins that provide structural support to cells and tissues, and what we produce less as we age.

If you’ve been thinking about skin treatment for ageing but are not ready to go under the knife, Rejuran is one option to consider. In this article, we will be focusing on Rejuran Healer, a form of Rejuran that is used for full-face rejuvenation. Here’s all you need to know about the procedure, from how it works and its benefits to the cost and length of treatment.

What is Rejuran?

Rejuran is a skin-healing treatment using polynucleotides from salmon DNA to rejuvenate and repair the skin. Originating from South Korea, it contains PN (polynucleotide), extracted from salmon, as the main active ingredient.

Salmon DNA was chosen because scientists found that it can accelerate the healing processes of skin cells, boosting collagen production, improving the skin barrier and enhancing wound healing. Salmon DNA is also similar to human DNA, ensuring there is little risk of an immune response when it is injected into the body.

There are three types of Rejuran available in Singapore:

  • Rejuran I – This treatment has a lower viscosity than the other Rejuran formulations, which makes it ideal for getting rid or wrinkles around the eyes and general under-eye rejuvenation.
  • Rejuran Healer –This treatment has a medium level of viscosity and can provide added hydration, which helps to strengthen the skin’s regenerative ability. It is ideal for full-face and neck rejuvenation.
  • Rejuran S – This treatment has the highest viscosity and is ideal for acne scar treatment, acting like a filler for depressed and sunken spots.


Rejuran Healer treatments in Singapore are typically used for general signs of ageing and marring of skin. The other Rejuran treatments are for targeted use.

How does Rejuran Healer work?

When Rejuran is administered, it triggers cell rejuvenation as the salmon DNA provides a 3D scaffolding structure for elastin and collagen growth.

How does Rejuran Healer work

At the same time, the Rejuran Healer reduces the appearance of sunken acne scars and minimises pores by repairing skin and collagen structures that were damaged by acne inflammation.

Benefits of Rejuran Healer Treatment

Unlike most skin booster treatments that work to draw water into the dermis to improve the skin’s hydration levels, a Rejuran Healer treatment works on a cellular level to bring about skin repair, healing and rejuvenation while stimulating the skin to produce your own collagen and elastin.

You can expect: 

  • Softer and smoother skin 
  • Improved skin elasticity from collagen production 
  • Reduced pore size
  • Reduced fine lines and wrinkles, especially around the eyes 
  • Reduced dark circles 

Clients who commit to Rejuran treatment for at least a few months can also expect a more defined face shape. However, do note that treatment results can vary with individuals.

What happens during a Rejuran Healer treatment?

During a Rejuran Healer treatment, the targeted area will be cleaned and numbing cream will be applied to it. The doctor will then administer the Rejuran healer injection into the superficial layers of the skin.

After the procedure, you will notice small bumps on the treated area. Don’t be alarmed by these bumps, as they should resolve by the next day. Otherwise, your doctor will prescribe an intense recovery cream and assist in “massaging” these bumps into your skin.

You will be advised on post-treatment care that involves massaging your skin over the next few days. The bumps and needle marks will subside after one to two days. Bruising is rare and if it occurs, typically resolves within a couple of days.

How much does Rejuran Healer cost?

The cost of a Rejuran Healer treatment in Singapore can vary from clinic to clinic. However, you can expect it to cost around $600 to $1,400 per session. At SL Aesthetic Clinic, the price estimate for a Rejuran healer treatment is $650.

How many treatments are needed for Rejuran Healer?

Each Rejuran Healer treatment consists of multiple injections from a 2ml syringe. Most doctors recommend 3-4 treatment sessions, spaced four weeks apart.

After these initial sessions, a single treatment can be repeated once every 6-12 months to maintain the effects of collagen stimulation and skin improvement.

Conditions that Rejuran Healer can Treat

Since Rejuran Healer works on a cellular level, it is effective in treating the following:

  • Depressed acne scars
  • Skin redness
  • Wrinkles and fine lines
  • Dry and oily skin
  • Skin dullness
  • Enlarged pores
  • Uneven skin tone
  • Irregular skin texture
  • Stretch marks
  • Dark eye circles
  • Sagging skin

For focused treatment of eye wrinkles and acne scars, your doctor may recommend Rejuran I and Rejuran S respectively for each condition.

Are there any side effects?

Rejuran is composed  of highly bio-compatible DNA fragments, it can work to fundamentally restore the skin without side effects. However, it may yield injection-related side effects, which are common for skin booster treatments. These include:

  • Redness of the skin
  • Needle marks
  • Slight bumps immediately after an injection
  • Itchiness
  • Mild bruising

Most of the time, the effects are minimal and temporary which should resolve within the day.

Who is suitable for Rejuran Healer?

Almost anyone looking to rejuvenate their ageing skin is a suitable candidate for Rejuran Healer treatment in Singapore, whether you want to prevent premature skin ageing, maintain your youthful appearance, restore your skin’s hydration, reduce acne scars or improve uneven skin texture.

The Rejuran Healer treatment, however, may not be suitable for vegans and vegetarians because of the presence of salmon DNA. It also may not be suitable for those who are allergic or especially sensitive to seafood.

Can Rejuran Healer be combined with other treatments?

A Rejuran Healer treatment can be combined with other treatments like laser therapies and chemical peels to achieve the effects that you are looking for. Repeated treatments can stimulate and optimise the vitality of specific cells that produce collagen and stabilise the physical and chemical conditions of the skin.

However, it should not be used if you have had cross-linked Hyaluronic Acid fillers as this may lead to granuloma formation, which can show up as hard nodules. This occurs when the polynucleotides in Rejuran react with BDDE – the chemical used for cross-linking in most Hyaluronic Acid fillers.

This also means that a Rejuran Healer treatment can be combined with skin boosters that contain non cross-linked Hyaluronic acid fillers and laser treatments like High-Intensity Focused Ultrasound (HIFU). In fact, Rejuran Healer enhances the effect of laser treatments for better results.

What’s the difference between Rejuran Healer, Profhilo, and Skin Boosters?

Rejuran Healer, Profhilo, and Skin Boosters are similar in terms of treatment delivery – they are all non-surgical, meaning they do not require any cuts in the skin or opening of skin tissue. However, they differ in composition and other ways, as listed below:

Rejuran Healer Profhilo Skinboosters
Main ingredient Polynucleotides BDDE-free Hyaluronic Acid Hyaluronic Acid
Purpose Skin repair, collagen formation  Skin hydration, skin bioremodelling Skin hydration, general glow and radiance 
Injection technique Micro injections administered manually or by an injector machine  5 injection points on each side of the face Micro injections administered manually or by an injector machine 
Recommended treatment protocol 3-4 sessions spaced 2-4 weeks apart 2 sessions spaced 1 month apart 2 sessions spaced 1 month apart 

Rejuran Healer Treatment Aftercare Tips 

Caring for your skin after a Rejuran Healer treatment can minimise the chances of injection-related side effects. Some of the steps you can take are listed below. :

  • Take herbal supplements such as arnica to reduce swelling.
  • Avoid strenuous activities that can trigger your sweat glands to produce sebum which counters the effect of your Rejuran Healer treatment.
  • Avoid alcohol and smoking as these can affect pores and your skin’s ability to heal.
  • Avoid exposure to intense heat as this can inhibit the healing effects of the Rejuran Healer.
  • Avoid waxing, chemical peels and energy-based treatments, as these may counter the effects of your Rejuran Healer treatment.

Final Thoughts

If you are considering a Rejuran Healer treatment in Singapore to reverse the signs of ageing or restore your youthful look, you should consult a qualified medical professional for proper advice and guidance. Here at SL Aesthetic Clinic, we’re happy to address any questions or concerns you have. So contact us today to book a consultation.


Is Rejuran Healer safe?

Yes, the main ingredient used in Rejuran, Salmon DNA, is biocompatible with human skin and has been extensively studied to be safe for use. 

How long do results last?

Results can last several months, but multiple sessions are recommended for optimal outcomes.

Is Rejuran treatment painful?

There is minimal pain – we apply numbing cream before commencing treatment to ensure you feel as comfortable as possible. 

Why are there big price differences between providers?

Some providers use topical treatments from the same brand name, not injectables. This affects cost and efficacy. If your provider offers you Rejuran treatment at a lower than average price, there is a high chance the Rejuran you are receiving is fake. To be safe, ensure the product is from the official distributor. Ask to see the label before treatment.

Is Rejuran good for your skin?

Yes, think of Rejuran as food for your skin – it feeds your skin with nucleotides. Nucleotides are building blocks of our DNA; they contain regenerative properties that significantly enhance the skin’s ability to repair and renew itself.

Can Rejuran be combined with Profhilo?

Yes, Rejuran and Profhilo can be done together as they work synergistically. However, they should be done strategically for maximum results. If you are interested in a holistic Rejuran and Profhilo combination treatment plan, please contact us for more information.

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